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Efficacy of surufatinib in advanced Grade 3 neuroendocrine tumors: a real-world, national, multicenter study.

Ther Adv Med Oncol · 2026 · PMC13428147 · PMID 42542772

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hedged sentence
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closest p · 1.6× alpha
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boldest claim

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a numerical trendp = 0.08so close (0.05 < p ≤ 0.1)
Combined treatment showed a numerical trend toward improved ORR (33.3% vs 16.0%, p = 0.08), but did not significantly prolong PFS compared to surufatinib monotherapy (9.7 vs 9.4 months, p = 0.64).

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