Although Rot treatment induced a decreasing trend in S-glutathionylation levels displayed, this effect did not reach statistical significance, whereas p75NTR modulation by LM11A-31 significantly increased GSH immunoreactivity compared to both control and rotenone-treated cells ( Figure 6B ).
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Pharmacological modulation of p75 neurotrophin receptor in microglial cells improves resilience to rotenone cytotoxicity.
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