Barely Significant
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Comparative evaluation of chitosan nanoparticles and ethylenediaminetetraacetic acid as intracanal irrigants and their effect on postoperative pain reduction in single-sitting root canal treatment - A randomized controlled trial.

J Conserv Dent Endod · 2026 · PMC13432046 · PMID 42549463

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highly significantno p-value reported
Results: Both groups demonstrated a highly significant, progressive pain reduction from baseline to 72 h.

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