Replication origin firing capacity indicates ATR inhibitor sensitivity.

Nat Commun · 2026 · PMC13434684 · PMID 42321192

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

highly significantno p-value reported

This revealed a highly significant enrichment of the DNA replication initiation signature (NES = 2.079, adjusted FDR q -value < 0.0197) in the sensitive patient-derived primary cells (Fig. 5A ).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.