Paradoxical angiogenic activation under anti-VEGF therapy: tip cell hyper-sprouting and vessel remodeling drive inefficient vascularization in multiscale tumor simulations.

BMC Cancer · 2026 · PMC13440003 · PMID 42226126

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highly significantno p-value reported

The apparent discrepancy between early stochastic divergence and highly significant endpoint differences arises from the model’s dynamical behavior.

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