Leveraging IGF signaling to improve the spatial organization and regenerative potential of iPSC-derived vascularized liver organoids.

Sci Adv · 2026 · PMC13440402 · PMID 42555733

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highly significantP = 2.76 × 10 −24actually significant

A test of homogeneity for the core matrisome proteins revealed a highly significant difference between native and dECM livers (χ 2 = 109.91, P = 2.76 × 10 −24 ), indicating that the relative abundance of core ECM components was markedly altered following decellularization.

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