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A preconception to late pregnancy community cohort study for reference values of serum thyrotropin and total thyroxine.

Front Endocrinol (Lausanne) · 2026 · PMC13441771 · PMID 42563989

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a decreasing trendno p-value reported
The 97.5th percentile for TSH shows a decreasing trend from 4.7 μIU/mL pre-pregnancy to 3.6 μIU/mL in the first trimester, followed by an increase to 3.9 μIU/mL in the second trimester.

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