Polyphyllin II attenuates renal fibrosis in diabetic kidney disease partly through regulation of autophagy and PI3K/AKT/mTOR signaling.

Front Pharmacol · 2026 · PMC13443031 · PMID 42564418

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a decreasing trendno p-value reported

PPII treatment partially improved these abnormalities, as evidenced by reduced UACR, Scr, and UA levels and increased Alb levels ( Figures 2G–I,K ), while BUN showed a decreasing trend ( Figure 2J ).

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