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Comparative Analysis of Bone Age Estimation Using the Manual Greulich and Pyle Method Versus Artificial Intelligence Algorithms in an Indian Pediatric Population Aged 1-18 Years.

Cureus · 2026 · PMC13446377 · PMID 42565162

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a possible trendno p-value reported
Figure 7 shows sex stratified MAE: Xrayhead performed worse in females (MAE 3.39 years) versus males (1.57 years), suggesting a possible trend toward sex-related variation; however, this finding should be interpreted cautiously because of the relatively small female subgroup.

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