Barely Significant
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Mechanical effects of heat-moisture exchangers in ventilated patients.

Crit Care · 1999 · PMC137236 · PMID 11094485

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may be significantno p-value reported
On the other hand, the alveolar hypoventilation that results from lack of compensation for the artificial nose dead space may be significant, especially in patients with the most severe alterations in respiratory mechanics, in whom the ventilatory treatment relies on low levels of minute ventilation.

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