Barely Significant
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Codon usage domains over bacterial chromosomes.

PLoS Comput Biol · 2006 · PMC1447655 · PMID 16683018

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highly significantno p-value reported
Deviations to the random values for those classes are highly significant, with z -scores all larger than 3.4 and soaring up to 6.5.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.