By 1 week after the initiation of differentiation (7 days after the start of NGF, exposure to 5 μM CPF for the final 3 days), there was a small decrement in DNA content at the margin of statistical significance ( p < 0.06) and no change in viability as assessed with trypan blue staining ( Figure 4A ).
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Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells.
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at the margin of significancep < 0.07
Activity per unit protein showed the same trend, although for this measure the TH effect was at the margin of significance ( p < 0.07) ( Figure 4C ).