Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.

y 2, mean body weight in ani- mals exposed to DES or OPP was reduced when compared to controls, whereas ani- mals exposed to either dose of OP were increased in size by 8% or more (Table 3). Except for animals exposed to the lower dose of OP (100 pg/I), all other treatment groups exhibited a highly significant decrease in absolute testis weight and in the ratio of testis/kidney size (Table 3); all treatment groups showed a significant decrease in relative testis weight.

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