Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins.

The differences in both cases are highly significant (p-values<0.001), and it is evident that PRODIV-TMHMM is highly unreliable for discrimination purposes, a fact noticed already in [ 13 ], followed by MEMSAT and UMDHMM TMHP , whereas HMM-TM and HMMTOP form a group of intermediate reliability just before the highly reliable for this task methods, TMHMM, Phobius, S-TMHMM and PRO-TMHMM.

also in 132,142 other papers

However, when comparing the number of correctly predicted topologies, there was a marginally significant difference with a p-value of 0.052.

also in 26,082 other papers