Prostate cancer cells show elevated urokinase receptor in a mouse model of metastasis.

Cancer Cell Int · 2006 · PMC1560166 · PMID 16928272

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These data confirmed a highly significant increase in uPAR positive cells in lymph node metastases compared with uPAR positive cells in the primary tumors (Figure 2C ) in each of the mice. uPAR confers increased migration and invasive properties to transfected PC-3M cells In order to begin to understand why uPAR might be enriched in lymph

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