Response of a phagocyte cell system to products of macrophage breakdown as a probable mechanism of alveolar phagocytosis adaptation to deposition of particles of different cytotoxicity.

uartz particles in lungs. First, the numbers of recruited alveolar mac- rophages (AM) are considerably higher with quartz than with the deposition of dust particles of low cytotoxicity (e.g., ferrous oxide or titanium dioxide) which agrees with the results obtained elsewhere (8). Second, highly significant differences are found in the number of neutrophile leukocytes (NL) in the same washings.

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