Barely Significant
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Gene expression analysis indicates extensive genotype-specific crosstalk between the conjugative F-plasmid and the E. coli chromosome.

BMC Microbiol · 2006 · PMC1590023 · PMID 16981998

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The sentences

highly significantp < 0.001actually significant
Even though the number of F-plasmid encoded genes is small, this difference is statistically highly significant (p < 0.001, Fisher's exact test), implying large differences between F-plasmid encoded and chromosomal genes.

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