Neurotoxic and pharmacokinetic responses to trichloroethylene as a function of exposure scenario.

Environ Health Perspect · 2000 · PMC1637762 · PMID 10807561

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may be significantno p-value reported

Recognizing that various PBPK models for TCE are avail- able, this project developed a PBPK model for TCE in Long-Evans rats for the following reasons: There may be significant strain dif- ferences in the pharmacokinetics of TCE (32), and the neurotoxicity data were collected in Long-Evans rats.

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