Autoinsertion of soluble oligomers of Alzheimer's Abeta(1-42) peptide into cholesterol-containing membranes is accompanied by relocation of the sterol towards the bilayer surface.

BMC Struct Biol · 2006 · PMC1657013 · PMID 17052343

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closest p · 0.0× alpha

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The sentences

highly significantP < 0.001actually significant

The 95% confidence limits of the experimental profiles (shown for regions corresponding to the maxima of the two difference peaks) were well separated, and the calculated fits showed a highly significant difference in the position of membrane cholesterol with and without the peptide (P < 0.001).

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