Wildtype epidermal growth factor receptor (Egfr) is not required for daily locomotor or masking behavior in mice.

One strong candidate for such a modifier mutation is retinal degeneration ( Pdeb rd 1 ), which is carried by the C3H/HeSnJ strain but not C57BL/6EiJ, and causes progressive and selective degeneration of photoreceptor cells [ 18 , 19 ]; the Pdeb rd 1 mutation alone has a highly significant effect on masking behavior [ 16 ].

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