Characterization of highly frequent epitope-specific CD45RA+/CCR7+/- T lymphocyte responses against p53-binding domains of the human polyomavirus BK large tumor antigen in HLA-A*0201+ BKV-seropositive donors.

J Transl Med · 2006 · PMC1660549 · PMID 17096832

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highly significantno p-value reported

A highly significant correlation between the extent of IFN-γ gene expression and the percent specific lysis elicited respectively by 3-hrs ex vivo and 3-week in vitro stimulated CD8+ T cells with all peptides selected from all five HLA-A*0201+ BKV LTag seropositive responders tested was indeed observed (Pearson's R = 0.820, p = 0.0001, Figure 3A ).

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