Position-dependent effects of locked nucleic acid (LNA) on DNA sequencing and PCR primers.

Nucleic Acids Res · 2006 · PMC1694044 · PMID 17071964

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closest p

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not quite significantno p-value reported

Although the interaction was not quite significant in the pair-wise comparison, we conservatively computed the LNA-5′ versus unmodified pair-wise F -statistic by dividing the LNA pattern mean square by the interaction mean square, as recommended by Sokal and Rohlf ( 34 ) and described in Material and Methods.

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