Barely Significant
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Increased susceptibility to repeated freeze-thaw cycles in Escherichia coli following long-term evolution in a benign environment.

BMC Evol Biol · 2006 · PMC1698501 · PMID 17147797

Europe PMCDOI
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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 0.0001actually significant
The difference in freeze-thaw mortality rates between ancestral and evolved rates is highly significant (two-tailed t-test with unequal variances, p < 0.0001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.