Barely Significant
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Using phylogeny to improve genome-wide distant homology recognition.

PLoS Comput Biol · 2007 · PMC1779300 · PMID 17238281

Europe PMCDOI
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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 2.2 × 10 −16actually significant
Fisher's exact test confirms that this difference in numbers is highly significant ( p < 2.2 × 10 −16 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.