Overall, the rosetting var protein structures are not highly related (Figure 1 ), although the DBL1α 1 domain is similar between the UpsA-linked R29var and IT4var60 predicted proteins, which may be significant because DBL1α 1 is an erythrocyte binding region in R29var [ 51 ].
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Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates.
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