Discrete profile comparison using information bottleneck.

BMC Bioinformatics · 2006 · PMC1810319 · PMID 16723011

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may not be significantno p-value reported

However, even when this distance is large, the difference between two alignments may not be significant if both choices' scores are nearly the same.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.