X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria.

PLoS Med · 2007 · PMC1820604 · PMID 17355169

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a possible trendno p-value reported

Nevertheless, cohort sizes from the Kela region were sufficiently large to detect a possible trend to protection against severe malaria in these individuals.

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highly significantno p-value reported

Pooled odds ratios from meta-analysis of our data and data from a previous study confirmed highly significant protection against severe malaria in hemizygous males but not in heterozygous females.

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