In vitro methylation of all promoter CpGs until bp +171 revealed a weak trend towards transcriptional deactivation being more pronounced in Saos-2 than in MG63 cells (Fig. 9C ).
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Sp1/Sp3 and DNA-methylation contribute to basal transcriptional activation of human podoplanin in MG63 versus Saos-2 osteoblastic cells.
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