The samples were split into two sets in order to save DNA and reduced genotyping costs: the first set ( n = 2,270 cases and 2,280 controls) was genotyped for all SNPs, and the second set ( n = 2,203 cases and 2,280 controls) were then tested for those SNPs that showed marginally significant associations in set 1 ( p -heterogeneity or p -trend < 0.1).
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Association between common variation in 120 candidate genes and breast cancer risk.
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