Barely Significant
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Positive and negative design in stability and thermal adaptation of natural proteins.

PLoS Comput Biol · 2007 · PMC1829478 · PMID 17381236

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highly significantno p-value reported
This analysis indeed reveals a non-monotonic shape: the parabolic fit in Figure 9 A highlights the highly significant non-monotonic nature of the dependence.

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