Protein coevolution and isoexpression in yeast macromolecular complexes.

RESULTS AND DISCUSSION In accordance with previous studies (Bloom and Adami [ 5 ] and references therein), we found a highly significant correlation between the mean E of the complexes and their mean K (Pearson's R = −0.45, p < 10 −6 , n = 94, using K Candida-Saccharomyces ).

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