borderline significanceP = 0.06
Carriers of the rs4149601 GG-genotype together with the rs2288774 CC-or CT-genotype, as compared to non-carriers of this combination, displayed significantly lower P-renin and borderline significance for systolic salt sensitivity (P = 0.06–0.08) whereas there was no significance in diastolic salt sensitivity and Nt-proANP ( Table 3 ).