Application of family-based association testing to assess the genotype-phenotype association involved in complex traits using single-nucleotide polymorphisms.

For chromosome 3, the average p -value was always greater than 0.05 except for SNPs B03T3056, B03T3057, and B03T3058, which had average p -values of 0.00002, 0.00074, and 0.0038, respectively, showing highly significant evidence for association (Figure 1B ).

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