Methods to test for association between a disease and a multi-allelic marker applied to a candidate region.

BMC Genet · 2005 · PMC1866838 · PMID 16451557

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hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < 0.0001actually significant

For testing the association using the proposed methods, we selected replicate 50 of the Danacaa population, because in this replicate marker D03S0127 showed highly significant linkage to the disease locus with a LOD score greater than 6 ( p < 0.0001).

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borderline significantno p-value reported

Marker D03S0125 showed borderline significant association with KPD.

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