Fully-spliced HIV-1 RNAs are reverse transcribed with similar efficiencies as the genomic RNA in virions and cells, but more efficiently in AZT-treated cells.

Retrovirology · 2007 · PMC1868081 · PMID 17474982

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highly significantno p-value reported

Such early transcriptional activity from non-integrated DNAs could be highly significant in HIV-1 infection since all protein products of the FSpl RNAs are particularly crucial to engage infection.

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