Guanines are a quartet's best friend: impact of base substitutions on the kinetics and stability of tetramolecular quadruplexes.

One should note that, due to the order of four chosen for the fits, a 1 billion-fold decrease in k on corresponds to a ‘less impressive’, but still highly significant, 1000-fold higher strand concentration required to obtain a similar proportion of quadruplex species after the same incubation time.

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