Can biomarkers identify women at increased stroke risk? The Women's Health Initiative Hormone Trials.

PLoS Clin Trials · 2007 · PMC1891725 · PMID 17571161

Europe PMC DOI

hedged sentences

0.0300

closest p · 0.6× alpha

0.0600

boldest claim

The sentences

marginally significantp = 0.03actually significant

However, only an interaction of D-dimer during follow-up interaction with HT and stroke was marginally significant ( p = 0.03).

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nearly reached significancep = 0.06so close (0.05 < p ≤ 0.1)

Of the 30 biomarkers studied, the p -value for interaction between biomarker level and treatment assignment in the pooled cohorts nearly reached significance for IL-6 ( p = 0.06) and was significant for PAP ( p = 0.02) ( Table 3 ).

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