On the origin of the translation system and the genetic code in the RNA world by means of natural selection, exaptation, and subfunctionalization.

41 we read that "these affinities are weak, only manifest as a statistical trend, and worst of all, are seen, mostly, for chemically complex amino acids like arginine or histidine, rather than simple ones, such as glycine or alanine, that would be readily produced abiogenically." This statement requires some elaboration.

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With the sole exception of glutamine, the aptamers for each amino acids were enriched for codon and/or anticodon triplets at a statistically highly significant level [ 104 - 106 ].

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