Serum TNF-alpha level predicts nonproliferative diabetic retinopathy in children.

Mediators Inflamm · 2007 · PMC1906713 · PMID 17641733

Europe PMC DOI

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extremely significantno p-value reported

Early detection of the individual tendency for development of diabetic retinopathy, especially before evident changes become visible at the fundus of the eye, is extremely significant in children and adolescent with DM type 1.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.