Formaldehyde at low concentration induces protein tau into globular amyloid-like aggregates in vitro and in vivo.

This may be significant to understand the mechanism of chronic damage caused by methanol toxicity and formaldehyde stress [18] , [28] .

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Thus when polymerized and attached to the mica surface, the change in height may not be significant whilst the change in lateral dimension will be relatively easier to measure.

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