Efficacy and safety of tiotropium in COPD patients in primary care--the SPiRiva Usual CarE (SPRUCE) study.

Respir Res · 2007 · PMC1913915 · PMID 17605774

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a numerical trendno p-value reported

Subanalysis of COPD exacerbations by severity of airflow obstruction according to NICE criteria at baseline also showed a numerical trend towards lower incidence in the tiotropium group compared with placebo across severity categories (Table 5 ).

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