Barely Significant
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Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish.

BMC Dev Biol · 2007 · PMC1950712 · PMID 17597528

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a decreasing trendno p-value reported
The effect of cyclopamine treatment showed a decreasing trend as development progressed (compare treatment at 48 h to 96 h).

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