Effect of megestrol acetate on weight loss induced by tumour necrosis factor alpha and a cachexia-inducing tumour (MAC16) in NMRI mice.

Br J Cancer · 1990 · PMC1971439 · PMID 2206950

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highly significantno p-value reported

At this concentration, megestrol acetate produced a highly significant reversal of the TNF-induced decrease in body weight, accompanied by a significant in- crease in both food and water intake (Table I), without an alteration in the sick appearance of the animals.

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