pNR-2/pS2 immunohistochemical staining in breast cancer: correlation with prognostic factors and endocrine response.

There was a highly significant association between positive oestrogen receptor status and immunohistochemical staining for pNR-2 (Table I, chi square= 7.57, P <0.01).

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Positive oestrogen recep- tor status has previously been shown to associate with low histological grade (McCarty et al., 1980; Hawkins et al., 1987) but correlations with tumour size are not well recog- nised: in the current series the correlation between oestrogen receptor status and tumour grade fell short of significance, but there was a significant association between positive oest- rogen receptor status and smaller tumour size (data not shown).

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