Social factors, diet and breast cancer in a northern Italian population.

When various levels of wine consumption were considered, a positive trend in risk was evident with increasing levels of exposure (test for trend: X2 =23.6, P=0.001), the point estimate increasing more than tenfold (with 95% lower confidence limit of about three) for more than half a liter/day.

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Allowance for all potential distorting factors reduced the RR estimates slightly to 1.5 and 3.2 respectively, and the linear trend remained highly significant.

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