Therapy with high dose recombinant alpha 2 interferon (IFN-alpha 2) produces a depression in natural killer cell cytotoxicity.

Br J Cancer · 1984 · PMC1976876 · PMID 6466539

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highly significantno p-value reported

Subsequent treatment maintained an elevated level for up to 9 months. Highly significant and consistant increase in the NK cell activity after a single or multiple injection of three million units of IFN-a2 to patients with low or medium pretreatment levels of NK cell activity were reported by Lotzova et al., (1982).

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