Statistical analysis showed that the presence of laminin-containing basement membranes was correlated with low histological grade (well-differentiated tumours), but not with stage (progression through the bowel wall and the development of lymph node metastases) and, in a highly significant way, with a reduced incidence of distant metastases and increased patient survival.
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Laminin and fibronectin in rectal adenocarcinoma: relationship to tumour grade, stage and metastasis.
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