A rather low mdrl gene expression was seen in adult ALL. Thus, in specimens originating from three relapsed state leukaemias poorly responding to chemotherapeutic treatment the expression levels were hardly significant at all (ALL 1, ALL 2, and the bone marrow sample ALL 4-1).
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Mdr1/P-glycoprotein, topoisomerase, and glutathione-S-transferase pi gene expression in primary and relapsed state adult and childhood leukaemias.
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