In addition, combining loci that are barely significant or narrowly miss the criteria for significance in multiple populations can clearly lead to strong observations of new loci or improved confidence in previously known loci.
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A simple method for combining genetic mapping data from multiple crosses and experimental designs.
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The sentences
This is particularly useful when a simple cross with highly significant loci is being considered since the software used to sort P-values (OutParser.py) runs in approximately N 2 time with respect to number of permutations.