Diagnostic X-ray and ultrasound exposure and risk of childhood cancer.

Consistent with previous studies, prenatal X-ray exposure was found to be associated with an 80% increased risk of childhood cancers, although the estimation was based on 4% and 2% exposed cases and controls and was only marginally statistically significant (P = 0.08).

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These charactenrs- tics were, therefore, adjusted for in all subsequent analyses. Parental preconception X-ray exposure Children of mothers reporting ten or more X-ray examina- tions throughout their life prior to conception had a 50% marginally significant increase in risk of total cancer com- pared with controls, and similar though non-significant excess for acute leukaemia and lymphoma (Table II).

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